Semaglutide vs. Tirzepatide: The Showdown at VIVE
- Jami Furniss

- Apr 10, 2025
- 2 min read
Updated: Apr 14, 2025
Let’s cut through the fluff (literally and figuratively). At VIVE Wellness & Aesthetics, we’re not about trends—we’re about results. And when it comes to weight management and metabolic health, two names are dominating the conversation: semaglutide and tirzepatide.
They’re not just buzzy—they’re biologically brilliant. But which one is the right fit for you? Let’s break it down like we do everything else at VIVE: clearly, confidently, and with just a touch of sass.
What Are We Dealing With Here?
Semaglutide
You might know it as Ozempic (for type 2 diabetes) or Wegovy (for weight loss).
It’s a GLP-1 receptor agonist, which is science speak for “this helps you feel full, eat less, and stabilize your blood sugar like a champ.”
It slows gastric emptying and curbs cravings. In short: it works with your body to stop the snack attacks.
Tirzepatide
Sold under names like Mounjaro and Zepbound.
It’s got double the punch: a GIP/GLP-1 receptor agonist. Translation? It mimics two hormones that help regulate insulin, reduce appetite, and boost fat metabolism.
Basically, it’s the overachiever in your biohacking toolbox.
Which One Works Better?
This isn’t a trick question—tirzepatide is showing stronger outcomes, especially for weight loss. Studies show people on tirzepatide lose more weight (up to 22.5% of their body weight!) than those on semaglutide (closer to 15%).
It also tends to have a slightly better impact on blood sugar levels, making it a solid pick for those juggling weight loss with metabolic issues.
But don’t sleep on semaglutide—it’s effective, well-studied, and beloved for a reason.
Side Effects:
Let’s be real—no one loves nausea, and both medications can bring it on. Other possible side effects include:
Bloating
Constipation or diarrhea (sometimes both, because bodies are wild)
Slower digestion
The occasional “what did I just eat?” moment
At VIVE, we customize your dosing and support you every step of the way to help minimize side effects while maximizing results.
The VIVE Verdict
Here’s how they stack up in our clinical experience:
So… Which One is Right for You?
That’s where we come in. At VIVE Wellness & Aesthetics, we look at your goals, your lifestyle, and your lab results—not just your BMI. Whether you're focused on weight loss, insulin resistance, or aging like a fine wine, we design a plan that actually fits your body.
And yes, it can include semaglutide or tirzepatide—prescribed thoughtfully, monitored professionally, and paired with lifestyle tools that support long-term success.
Ready to meet your metabolic match? Let’s chat. Book a consult today, and let’s make your goals the next before-and-after story worth bragging about.






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